Glossary

Osteoporosis

A bone disease in which bone density and strength decrease, making bones fragile and more likely to break. It often causes no symptoms until a fracture happens.

Osteoporosis is a condition where bones lose mass and density, or their internal structure weakens, so they break more easily. The National Institute of Arthritis and Musculoskeletal and Skin Diseases calls it a "silent" disease because many people have no symptoms until they fracture a hip, wrist, or vertebra, sometimes from a minor fall or even a cough.

Risk rises with age, especially for women after menopause, and with low calcium and vitamin D, low body weight, smoking, heavy drinking, some medical conditions, and certain medicines. Doctors diagnose it with a bone density scan (DXA), and treatment can include medicines, supplements, exercise, and fall prevention.

Osteoporosis matters in litigation when a drug is alleged to have caused bone loss or fractures without adequate warning. One well-known example is the injectable contraceptive Depo-Provera. Depo-Provera's FDA-approved label carries a boxed warning titled "Loss of Bone Mineral Density," stating that women who use it may lose significant bone mineral density. The current Depo-Provera lawsuits focus on a different injury, meningioma brain tumors, but the bone warning shows how a label's contents become central evidence in drug cases: a warning that was given can defeat a claim, and a missing one can support it.

If you believe a medicine contributed to bone loss or fractures, keep your bone density results and pharmacy records, which show how long you took the drug. See our Depo-Provera lawsuit page and the guide to class actions versus mass torts.

Sources.

Statutes, court rules, appellate opinions, and bar publications we relied on. See our editorial standards.

  1. 1.NIAMS: Osteoporosis
  2. 2.Pfizer: Depo-Provera CI prescribing information